Clinical Images and Case Reports

An Unusual Presentation of Giant Cell Arteritis Mimicking Stroke: A Case Report with Clinical Images

2025-02-26T07:43:58+00:00

Giant Cell Arteritis (GCA) is a systemic vasculitis that primarily affects medium and large arteries, predominantly in older adults. Although classic symptoms include headache, jaw claudication, and vision disturbances, GCA can present atypically, leading to diagnostic challenges. We report a rare case of GCA mimicking an acute ischemic stroke in a 72-year-old female who presented with sudden-onset unilateral weakness and dysarthria. Initial neuroimaging ruled out cerebral infarction, prompting further vascular assessment. Temporal artery biopsy confirmed the diagnosis of GCA, and the patient responded well to corticosteroid therapy. This case highlights the importance of considering GCA in the differential diagnosis of stroke-mimicking syndromes, especially in elderly patients, to prevent irreversible complications. The report includes detailed clinical images illustrating key diagnostic findings.

Clinical Images in Rare Pediatric Dermatomyositis: A Diagnostic Challenge

2025-02-26T07:49:46+00:00

Juvenile Dermatomyositis (JDM) is a rare autoimmune inflammatory myopathy primarily affecting children. It is characterized by proximal muscle weakness and distinctive cutaneous findings. Early and accurate diagnosis is essential to prevent complications such as calcinosis, muscle atrophy, and systemic involvement. However, JDM often presents diagnostic challenges due to its varied and sometimes subtle clinical manifestations. This case report presents a pediatric patient with an unusual dermatologic presentation of JDM, supported by detailed clinical images. The discussion highlights key diagnostic criteria, differential diagnoses, and the role of imaging and histopathological analysis in confirming the diagnosis. By emphasizing clinical recognition and early intervention, this report underscores the importance of multidisciplinary approaches in managing rare pediatric autoimmune diseases.

Unilateral Optic Neuritis: Clinical Imaging Findings and Differential Diagnosis

2025-02-26T07:53:37+00:00

Unilateral optic neuritis (ON) is an inflammatory condition affecting the optic nerve, often presenting with acute vision loss, pain on eye movement, and dyschromatopsia. It may occur in isolation or as a manifestation of underlying demyelinating, infectious, or autoimmune disorders. Magnetic resonance imaging (MRI) plays a crucial role in diagnosing ON and distinguishing between etiologies such as multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and infectious or paraneoplastic causes. This case-based review presents the clinical and imaging findings of unilateral ON, emphasizing key radiological features that aid in differential diagnosis. We discuss the importance of early recognition and appropriate management to prevent permanent visual impairment.

Case Report and Clinical Images of an Atypical Manifestation of Lupus Nephritis

2025-02-26T07:57:06+00:00

Lupus nephritis (LN) is a severe renal complication of systemic lupus erythematosus (SLE) that presents with a broad spectrum of clinical and histopathological manifestations. While classical presentations include proteinuria, hematuria, and renal dysfunction, atypical cases can mimic other glomerular diseases, leading to diagnostic challenges. This case report describes a rare manifestation of LN in a young female presenting with nephrotic-range proteinuria and minimal immune complex deposition on renal biopsy. Clinical images, including histopathology and immunofluorescence findings, are provided to illustrate the diagnostic complexity. The report highlights the importance of a multidisciplinary approach in evaluating unusual LN presentations and emphasizes the role of repeat biopsy and advanced serological markers in challenging cases.

Case Report of Atypical Hemolytic Uremic Syndrome in a Young Norwegian Male

2025-02-26T08:25:55+00:00

Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening thrombotic microangiopathy characterized by complement dysregulation. This report presents a 19-year-old male from Oslo, Norway, who developed severe anemia, thrombocytopenia, and acute kidney injury following a viral infection. Complement factor mutations were identified, confirming aHUS. Eculizumab therapy led to rapid hematologic and renal recovery. This case highlights the importance of early diagnosis and targeted treatment in aHUS.

Unusual Presentation of Giant Cell Arteritis with Ischemic Optic Neuropathy: A Case Report

2025-02-26T08:28:28+00:00

Giant Cell Arteritis (GCA) is an inflammatory vasculopathy primarily affecting the elderly. This case report discusses a 72-year-old female from Beijing, China, who presented with sudden vision loss in her left eye. Initial MRI and biopsy confirmed GCA-associated ischemic optic neuropathy. Immediate corticosteroid therapy led to partial visual recovery. This case highlights the need for early detection and intervention in GCA to prevent irreversible complications.

A Rare Case of Tuberculous Spondylitis with Atypical Symptoms in an Immunocompromised Patient

2025-02-26T08:30:54+00:00

Tuberculous spondylitis (Pott’s disease) is a rare but severe extrapulmonary tuberculosis manifestation. This report presents a 55-year-old immunocompromised male from Russia with lower back pain, fever, and neurological deficits. MRI revealed vertebral collapse at T8-T9, and biopsy confirmed Mycobacterium tuberculosis. The patient was managed with anti-tubercular therapy and surgical stabilization. This case emphasizes the need for early imaging and microbiological confirmation in high-risk individuals.

An Uncommon Presentation of Cardiac Hydatid Disease in a Brazilian Patient

2025-02-26T08:33:05+00:00

Cardiac hydatid disease is a rare manifestation of echinococcosis, often leading to severe cardiac complications. This report presents a 45-year-old male from São Paulo, Brazil, who was admitted with progressive dyspnea and chest pain. Echocardiography and MRI revealed a large hydatid cyst in the left ventricle. Surgical removal was performed successfully, followed by albendazole therapy. This case highlights the importance of early diagnosis and multidisciplinary management of cardiac hydatid disease.

Multisystem Inflammatory Syndrome in an Adult Post-COVID-19: A Case Study from Iran

2025-02-26T08:35:45+00:00

Multisystem inflammatory syndrome in adults (MIS-A) is a rare but severe complication of COVID-19. This case report presents a 38-year-old male from Tehran, Iran, who developed high-grade fever, myocarditis, and multi-organ dysfunction three weeks after recovering from mild COVID-19. Echocardiography and inflammatory markers confirmed MIS-A. Treatment with intravenous immunoglobulin (IVIG) and corticosteroids led to full recovery. This case underscores the importance of recognizing post-viral inflammatory syndromes for early intervention.

A Case of Autoimmune Encephalitis Mimicking Neuropsychiatric Lupus: German Case Report

2025-02-26T08:37:55+00:00

Autoimmune encephalitis is a challenging diagnosis, often mimicking neuropsychiatric disorders such as lupus. This report presents a 42-year-old female from Berlin, Germany, who exhibited confusion, seizures, and psychiatric symptoms. CSF analysis and anti-NMDA receptor antibodies confirmed autoimmune encephalitis. High-dose corticosteroids and plasmapheresis resulted in a significant neurological improvement. This case highlights the importance of early recognition and targeted immunotherapy.

A Rare Presentation of Adrenal Insufficiency Due to Tuberculosis: A French Case Report

2025-02-26T08:39:56+00:00

Tuberculosis (TB) remains a significant health issue, particularly in immunocompromised individuals. This report presents a 50-year-old male from Paris, France, who developed progressive fatigue, weight loss, and hypotension. Endocrine evaluation revealed primary adrenal insufficiency, and imaging confirmed adrenal tuberculosis. Anti-TB therapy and corticosteroid replacement led to symptom resolution. This case underscores the importance of considering TB in cases of unexplained adrenal insufficiency.

Unusual Case of Severe Anaphylaxis to Seafood in a Young Canadian Patient

2025-02-26T08:41:44+00:00

Seafood allergy is a common cause of anaphylaxis, but severe and atypical presentations are rare. This report presents a 27-year-old male from Toronto, Canada, who experienced anaphylactic shock after consuming shrimp. Despite epinephrine administration, the patient required intensive care for persistent hypotension. Comprehensive allergy testing confirmed specific IgE reactivity to shellfish proteins. The case highlights the necessity of rapid intervention and long-term desensitization strategies.

Atypical Presentation of Spontaneous Pneumothorax in a South Korean Teenager

2025-02-26T08:43:48+00:00

Spontaneous pneumothorax (SP) is a common emergency in adolescents, yet atypical presentations can delay diagnosis. This report details a 16-year-old male from Seoul, South Korea, who presented with progressive chest discomfort and exertional dyspnea. Initial chest X-ray showed a small apical pneumothorax, but a subsequent CT scan revealed extensive subpleural blebs. The patient underwent video-assisted thoracoscopic surgery (VATS) with pleurodesis. This case underscores the importance of considering SP even in patients with minimal symptoms.

Uncommon Presentation of Osteomyelitis in a Diabetic Dutch Patient: A Case Report

2025-02-26T08:45:53+00:00

Osteomyelitis is a severe complication of diabetes, often presenting insidiously. This report describes a 62-year-old male from Amsterdam, Netherlands, who presented with chronic foot pain and swelling. Despite normal inflammatory markers, MRI revealed osteomyelitis in the first metatarsal. Surgical debridement and a six-week antibiotic regimen resulted in successful recovery. This case underscores the need for early imaging in diabetic foot infections.

Case Report of Atypical Hemolytic Uremic Syndrome in a Young Norwegian Male

2025-02-26T08:47:55+00:00