Sickle Cell Disease Presenting with Acute Chest Syndrome in a Ghanaian Patient

Abstract

Sickle cell disease (SCD) is a significant health burden in sub-Saharan Africa. This case report describes a 25-year-old male from Accra, Ghana, who presented with severe chest pain, dyspnea, and hypoxia. Chest X-ray and CT imaging revealed acute chest syndrome, a severe complication of SCD. The patient was managed with oxygen therapy, blood transfusion, and hydroxyurea, leading to clinical improvement. This case underscores the need for early recognition and treatment of life-threatening SCD complications.