Evaluation of Heat-Killed Mycobacterium was an Immunomodulatory Add-On Therapy in Moderate to Severe COVID-19 Patients

Abstract

This study evaluates the therapeutic potential of heat-killed Mycobacterium w as an immunomodulatory add-on treatment in hospitalized patients with moderate to severe COVID-19. A randomized cohort of patients received standard of care with or without Mycobacterium w. Outcomes assessed included oxygen requirement, cytokine profile modulation, duration of hospital stay, and mortality. The Mycobacterium w group demonstrated significantly reduced inflammatory markers and faster clinical recovery. This finding supports its role as a beneficial adjunct in COVID-19 management.