Narrow Band Imaging for Endoscopic Assessment of Neoangiogenesis in Laryngeal Lesions: A Case Report

Abstract

Neoangiogenesis is a key hallmark of malignant transformation in laryngeal lesions and plays a critical role in early diagnosis and management planning. Narrow Band Imaging (NBI), an advanced endoscopic technique that enhances mucosal and vascular patterns, has demonstrated improved accuracy in the detection of neoplastic changes compared to conventional white light endoscopy. We present a case of a middle-aged male with persistent hoarseness, whose laryngeal lesion was initially inconclusive under white light laryngoscopy. Subsequent evaluation using NBI revealed irregular, tortuous intrapapillary capillary loops suggestive of neoangiogenesis. Targeted biopsy confirmed the presence of early-stage glottic carcinoma. The use of NBI in this case not only facilitated accurate lesion demarcation but also guided optimal biopsy site selection, ultimately improving diagnostic precision. This case highlights the clinical utility of NBI in the endoscopic assessment of suspicious laryngeal lesions and supports its integration into routine otolaryngologic practice for early cancer detection.